SNEDDS AS LIPID-BASED NANOCARRIER SYSTEMS: CONCEPTS AND FORMULATION INSIGHTS

Formulation Optimization of Erythromycin Solid Lipid Nanocarrier Using Response Surface Methodology

In present work response surface methodology (RSM) using the miscellaneous design model was used to optimize formulations of erythromycin solid lipid nanocarriers (ERY-SLN). Two-factor three level factorial design was considered for optimization. There were three parameters, drug entrapment efficiency (EE), drug loading (DL) percentage, and mean particle size of ERY-SLN, considered for investig...

Innovative Nanocarrier Systems for the Delivery of Temoporfin: In Vitro Selection and Formulation Refinement

Mannan as a Promising Bioactive Material for Drug Nanocarrier Systems

Formulation Development and Evaluation of Hybrid Nanocarrier for Cancer Therapy: Taguchi Orthogonal Array Based Design

Taguchi orthogonal array design is a statistical approach that helps to overcome limitations associated with time consuming full factorial experimental design. In this study, the Taguchi orthogonal array design was applied to establish the optimum conditions for bovine serum albumin (BSA) nanocarrier (ANC) preparation. Taguchi method with L9 type of robust orthogonal array design was adopted to...

Nanocarrier based transdermal formulation of NSAID: Optimization of drug loading and analysis of permeation characteristics

Arthritis is a major cause of disability and morbidity, particularly in older individuals. The symptoms and signs of arthritis and related conditions include pain, stiffness, swelling, muscle weakness, and limitation of movement of the joints. The objective of the present work was to provide a dosage form for localized action of drugs used in treatment of arthritis to the affected tissues for p...